NFIL3 antibody (AA 133-462)

Catalog No. ABIN7161775

This anti-NFIL3 antibody is a Rabbit Polyclonal antibody detecting NFIL3 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for NFIL3 antibody (AA 133-462) (ABIN7161775)

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFIL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NFIL3 Antibody

Binding Specificity: AA 133-462

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Nuclear factor interleukin-3-regulated protein (133-462AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NFIL3

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Alternative Name: NFIL3

Background:

Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5\\\'-[GA]TTA[CT]GTAA[CT]-3\\\', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity).

Aliases: E4 promoter binding protein 4 antibody, E4 promoter-binding protein 4 antibody, E4BP 4 antibody, E4BP4 antibody, E4BP4 protein antibody, IL3BP 1 antibody, IL3BP1 antibody, Interleukin 3 binding protein 1 antibody, Interleukin 3 promoter transcriptional activator antibody, Interleukin-3 promoter transcriptional activator antibody, Interleukin-3-binding protein 1 antibody, NFIL 3 antibody, NFIL 3A antibody, NFIL3 antibody, NFIL3_HUMAN antibody, NFIL3A antibody, Nuclear factor interleukin 3 regulated antibody, Nuclear factor interleukin-3-regulated protein antibody, Transcriptional activator NF IL3A antibody, Transcriptional activator NF-IL3A antibody

UniProt: Q16649