NFATC1 antibody (AA 48-406)

Catalog No. ABIN7161789

The Rabbit Polyclonal anti-NFATC1 antibody has been validated for IHC, ELISA and IF. It is suitable to detect NFATC1 in samples from Human.

Quick Overview for NFATC1 antibody (AA 48-406) (ABIN7161789)

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-NFATC1 Antibody

Binding Specificity: AA 48-406

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 protein (48-406AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:1000-1:2000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Alternative Name: NFATC1

Background:

Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Aliases: cytoplasmic 1 antibody, MGC138448 antibody, NF ATc antibody, NF ATc1 antibody, NF-ATc antibody, NF-ATc1 antibody, NF-ATc1.2 antibody, NFAC1_HUMAN antibody, NFAT 2 antibody, NFAT transcription complex cytosolic component antibody, NFATC 1 antibody, NFATc antibody, NFATc1 antibody, Nuclear factor of activated T cells cytoplasmic 1 antibody, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody, Nuclear factor of activated T cells cytosolic component 1 antibody, nuclear factor of activated T-cells 'c' antibody, Nuclear factor of activated T-cells antibody

UniProt: O95644

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway