Osteocrin antibody (AA 28-133)

Catalog No. ABIN7162313

Product Details anti-Osteocrin Antibody

Target: Osteocrin (OSTN)

Binding Specificity: AA 28-133

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteocrin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Osteocrin protein (28-133aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Osteocrin

Target: Osteocrin (OSTN)

Alternative Name: OSTN (OSTN Products)

Synonyms: DKFZp459H195 antibody, MUSCLIN antibody, Ostc antibody, osteocrin antibody, OSTN antibody, Ostn antibody

Background:

Background: Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).

Aliases: Osteocrin (Musclin) [Cleaved into: Processed Osteocrin], OSTN

UniProt: P61366

Pathways: Hormone Activity