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SIN3B antibody (AA 705-769)

SIN3B Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7162487
  • Target See all SIN3B Antibodies
    SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 705-769
    Reactivity
    • 35
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 33
    • 4
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIN3B antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
    Isotype
    IgG
    Top Product
    Discover our top product SIN3B Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
    Alternative Name
    SIN3B (SIN3B Products)
    Synonyms
    fj63d08 antibody, si:dkey-6n6.6 antibody, wu:fj63d08 antibody, 2810430C10Rik antibody, SIN3 transcription regulator family member B antibody, SIN3 transcription regulator family member B S homeolog antibody, transcriptional regulator, SIN3B (yeast) antibody, sin3b antibody, SIN3B antibody, sin3b.S antibody, Sin3b antibody
    Background

    Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

    Aliases: SIN3B antibody, KIAA0700 antibody, Paired amphipathic helix protein Sin3b antibody, Histone deacetylase complex subunit Sin3b antibody, Transcriptional corepressor Sin3b antibody

    UniProt
    O75182
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