SIN3B antibody (AA 705-769) (Biotin)

Catalog No. ABIN7162488

The Rabbit Polyclonal anti-SIN3B antibody has been validated for ELISA. It is suitable to detect SIN3B in samples from Human.

Quick Overview for SIN3B antibody (AA 705-769) (Biotin) (ABIN7162488)

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIN3B antibody is conjugated to Biotin

Application: ELISA

Product Details anti-SIN3B Antibody (Biotin)

Binding Specificity: AA 705-769

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SIN3B

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Alternative Name: SIN3B

Background:

Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

Aliases: SIN3B antibody, KIAA0700 antibody, Paired amphipathic helix protein Sin3b antibody, Histone deacetylase complex subunit Sin3b antibody, Transcriptional corepressor Sin3b antibody

UniProt: O75182