PICALM antibody (AA 517-624) (Biotin)

Catalog No. ABIN7163231

This Rabbit Polyclonal antibody specifically detects PICALM in ELISA. It exhibits reactivity toward Human.

Quick Overview for PICALM antibody (AA 517-624) (Biotin) (ABIN7163231)

Target: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PICALM antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PICALM Antibody (Biotin)

Binding Specificity: AA 517-624

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylinositol-binding clathrin assembly protein (517-624AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PICALM

Target: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Alternative Name: PICALM

Background:

Background: Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.

Aliases: CALM antibody, Clathrin assembly lymphoid myeloid leukemia antibody, Clathrin assembly lymphoid myeloid leukemia protein antibody, CLTH antibody, LAP antibody, Phosphatidylinositol-binding clathrin assembly protein antibody, PICAL_HUMAN antibody, PICALM antibody

UniProt: Q13492

Pathways: Synaptic Membrane