PHLDA3 antibody (AA 43-95) (FITC)
Quick Overview for PHLDA3 antibody (AA 43-95) (FITC) (ABIN7163673)
Target
See all PHLDA3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 43-95
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Purpose
- PHLDA3 Antibody, FITC conjugated
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Purification
- Protein G purified
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Purity
- >95 %
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Immunogen
- Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Alternative Name
- PHLDA3
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Background
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Background: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Aliases: PHLA3_HUMAN antibody, PHLDA 3 antibody, phlda3 antibody, Pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology like domain family A member 3 antibody, Pleckstrin homology-like domain family A member 3 antibody, TDAG51/Ipl homolog 1 antibody, TDAG51/Ipl homologue 1 antibody, TIH 1 antibody, TIH1 antibody
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UniProt
- Q9Y5J5
Target
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