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PHLDA3 antibody (N-Term)

PHLDA3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN632801
  • Target See all PHLDA3 Antibodies
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 21
    • 7
    • 7
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 19
    • 1
    • 1
    Rabbit
    Clonality
    • 20
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHLDA3 antibody is un-conjugated
    Application
    • 11
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    PHLDA3 antibody was raised against the N terminal of PHLDA3
    Purification
    Affinity purified
    Immunogen
    PHLDA3 antibody was raised using the N terminal of PHLDA3 corresponding to a region with amino acids LQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRC
    Top Product
    Discover our top product PHLDA3 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PHLDA3 Blocking Peptide, catalog no. 33R-5324, is also available for use as a blocking control in assays to test for specificity of this PHLDA3 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHLDA3 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Alternative Name
    PHLDA3 (PHLDA3 Products)
    Synonyms
    TIH1 antibody, Tih1 antibody, si:dz182n13.5 antibody, zgc:92333 antibody, pleckstrin homology like domain family A member 3 antibody, pleckstrin homology like domain, family A, member 3 antibody, pleckstrin homology-like domain, family A, member 3 antibody, PHLDA3 antibody, Phlda3 antibody, phlda3 antibody
    Background
    PHLDA3 is a p53/TP53-regulated repressor of Akt/AKT1 signaling. It represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity.
    Molecular Weight
    14 kDa (MW of target protein)
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