PARP3 antibody (AA 1-240) (FITC)
Quick Overview for PARP3 antibody (AA 1-240) (FITC) (ABIN7163753)
Target
See all PARP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-240
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Poly [ADP-ribose] polymerase 3 protein (1-240AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
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Alternative Name
- PARP3
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Background
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Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Aliases: ADP ribosyltransferase (NAD+, poly (ADP ribose) antibody, ADP ribosyltransferase diphtheria toxin like 3 antibody, ADPRT-3 antibody, ADPRT3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD3 antibody, hPARP 3 antibody, hPARP-3 antibody, hPARP3 antibody, IRT 1 antibody, IRT1 antibody, NAD(+) ADP ribosyltransferase 3 antibody, NAD(+) ADP-ribosyltransferase 3 antibody, NAD+ ADP ribosyltransferase 3 antibody, pADPRT 3 antibody, pADPRT-3 antibody, pADPRT3 antibody, PARP 3 antibody, PARP-3 antibody, PARP3 antibody, PARP3_HUMAN antibody, Poly (ADP ribose) polymerase family, member 3 antibody, Poly (ADP ribose) synthetase 3 antibody, Poly [ADP-ribose] polymerase 3 antibody, Poly[ADP ribose] synthetase 3 antibody, Poly[ADP-ribose] synthase 3 antibody
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UniProt
- Q9Y6F1
Target
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