GALNT11 antibody (AA 420-606)
Quick Overview for GALNT11 antibody (AA 420-606) (ABIN7163856)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 420-606
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 11 protein (420-606AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GALNT11 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11))
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Alternative Name
- GALNT11
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Background
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Background: Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO).
Aliases: A430075I06Rik antibody, AI648252 antibody, E430002F06Rik antibody, FLJ21634 antibody, GalNAc Transferase 11 antibody, GalNAc-T11 antibody, GalNAcT11 antibody, GALNT11 antibody, GLT11_HUMAN antibody, MGC71630 antibody, Polypeptide GalNAc transferase 11 antibody, Polypeptide N-acetylgalactosaminyltransferase 11 antibody, pp-GaNTase 11 antibody, Protein-UDP acetylgalactosaminyltransferase 11 antibody, tcag7.1057 antibody, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11 antibody, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) antibody
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UniProt
- Q8NCW6
Target
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