GALNT11 antibody (AA 420-606) (Biotin)

Catalog No. ABIN7163857

Product Details anti-GALNT11 Antibody (Biotin)

Target: GALNT11 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11))

Binding Specificity: AA 420-606

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNT11 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 11 protein (420-606AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GALNT11

Target: GALNT11 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11))

Alternative Name: GALNT11 (GALNT11 Products)

Synonyms: A430075I06Rik antibody, AI648252 antibody, E430002F06Rik antibody, GALNACT11 antibody, polypeptide N-acetylgalactosaminyltransferase 11 antibody, Galnt11 antibody, GALNT11 antibody

Background:

Background: Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO).

Aliases: A430075I06Rik antibody, AI648252 antibody, E430002F06Rik antibody, FLJ21634 antibody, GalNAc Transferase 11 antibody, GalNAc-T11 antibody, GalNAcT11 antibody, GALNT11 antibody, GLT11_HUMAN antibody, MGC71630 antibody, Polypeptide GalNAc transferase 11 antibody, Polypeptide N-acetylgalactosaminyltransferase 11 antibody, pp-GaNTase 11 antibody, Protein-UDP acetylgalactosaminyltransferase 11 antibody, tcag7.1057 antibody, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11 antibody, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) antibody

UniProt: Q8NCW6