RNF212 antibody (AA 1-297)

Catalog No. ABIN7164415

Product Details anti-RNF212 Antibody

Target: RNF212 (Ring Finger Protein 212 (RNF212))

Binding Specificity: AA 1-297

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF212 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Probable E3 SUMO-protein ligase RNF212 protein (1-297AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF212

Target: RNF212 (Ring Finger Protein 212 (RNF212))

Alternative Name: RNF212 (RNF212 Products)

Synonyms: ZHP3 antibody, ring finger protein 212 antibody, RNF212 antibody

Background:

Background: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity).

Aliases: FLJ38841 antibody, Hypothetical protein LOC285498 antibody, LOC285498 antibody, OTTHUMP00000147525 antibody, Probable E3 SUMO-protein ligase RNF212 antibody, RING finger protein 212 antibody, RN212_HUMAN antibody, RNF 212 antibody, RNF212 antibody, ZHP3 antibody, ZHP3, C. elegans, homolog of antibody, ZIP3-related protein antibody

UniProt: Q495C1