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PSMA7 antibody (AA 5-232) (HRP)

PSMA7 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7164967
$328.90
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  • Target See all PSMA7 Antibodies
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Binding Specificity
    • 5
    • 1
    • 1
    AA 5-232
    Reactivity
    • 10
    • 4
    • 1
    Human
    Host
    • 9
    • 1
    Rabbit
    Clonality
    • 9
    • 1
    Polyclonal
    Conjugate
    • 6
    • 3
    • 1
    This PSMA7 antibody is conjugated to HRP
    Application
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Proteasome subunit alpha type-7 protein (5-232AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Alternative Name
    PSMA7 (PSMA7 Products)
    Synonyms
    C6 antibody, HSPC antibody, RC6-1 antibody, XAPC7 antibody, C6-I antibody, DDBDRAFT_0185059 antibody, DDBDRAFT_0217080 antibody, DDB_0185059 antibody, DDB_0217080 antibody, hspc antibody, rc6-1 antibody, xapc7 antibody, psma7 antibody, proteasome subunit alpha 7 antibody, proteasome (prosome, macropain) subunit, alpha type 7 antibody, 20S proteasome subunit alpha-7 antibody, proteasome subunit alpha 7 S homeolog antibody, PSMA7 antibody, Psma7 antibody, psmA7 antibody, psma7 antibody, psma7.S antibody
    Background

    Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response

    Aliases: C6 antibody, HSPC antibody, MGC3755 antibody, OTTHUMP00000031449 antibody, OTTHUMP00000031450 antibody, OTTHUMP00000031453 antibody, Proteasome (prosome macropain) subunit alpha type 7 antibody, Proteasome alpha 7 subunit antibody, Proteasome subunit alpha 4 antibody, Proteasome subunit alpha type 7 antibody, Proteasome subunit alpha type-7 antibody, Proteasome subunit RC6 1 antibody, Proteasome subunit RC6-1 antibody, Proteasome subunit XAPC7 antibody, PSA7_HUMAN antibody, PSMA 7 antibody, PSMA7 antibody, RC6 1 antibody, XAPC7 antibody

    UniProt
    O14818
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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