PRMT7 antibody (AA 285-390) (Biotin)

Catalog No. ABIN7165084

This anti-PRMT7 antibody is a Rabbit Polyclonal antibody detecting PRMT7 in ELISA. Suitable for Human.

Quick Overview for PRMT7 antibody (AA 285-390) (Biotin) (ABIN7165084)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT7 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PRMT7 Antibody (Biotin)

Binding Specificity: AA 285-390

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein arginine N-methyltransferase 7 protein (285-390AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7

Background:

Background: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 \'Arg-3\' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.

Aliases: [Myelin basic protein]-arginine N-methyltransferase PRMT7 antibody, ANM7_HUMAN antibody, FLJ10640 antibody, Histone-arginine N-methyltransferase PRMT7 antibody, KIAA1933 antibody, Myelin basic protein arginine N methyltransferase antibody, OTTHUMP00000174863 antibody, PRMT7 antibody, Protein arginine methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization