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EIF2C3 antibody (AA 251-400) (FITC)

EIF2C3 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7165097
$328.90
Plus shipping costs $45.00
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  • Target See all EIF2C3 Antibodies
    EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
    Binding Specificity
    • 3
    • 1
    • 1
    AA 251-400
    Reactivity
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 6
    • 1
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    This EIF2C3 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein argonaute-3 protein (251-400aa)
    Isotype
    IgG
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
    Alternative Name
    AGO3 (EIF2C3 Products)
    Synonyms
    EIF2C3 antibody, Eif2c3 antibody, Argonaute3 antibody, ago3 antibody, eif2c3 antibody, eif2c3b antibody, si:dkey-3n22.3 antibody, AW048688 antibody, C130014L07Rik antibody, ARGONAUTE 3 antibody, T19E23.8 antibody, T19E23_8 antibody, argonaute 3, RISC catalytic component antibody, argonaute RISC catalytic component 3b antibody, argonaute RISC catalytic subunit 3 antibody, argonaute RISC catalytic component 3 antibody, ARGONAUTE 3 antibody, AGO3 antibody, Ago3 antibody, ago3b antibody
    Background

    Background: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

    Aliases: Protein argonaute-3 (Argonaute3) (hAgo3) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3), AGO3, EIF2C3

    UniProt
    Q9H9G7
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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