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BICD2 antibody (AA 511-625) (HRP)

BICD2 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7165143
  • Target See all BICD2 Antibodies
    BICD2 (Bicaudal D Homolog 2 (BICD2))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 511-625
    Reactivity
    • 24
    • 5
    • 5
    • 2
    • 2
    Human
    Host
    • 22
    • 2
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BICD2 antibody is conjugated to HRP
    Application
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    BICD2 (Bicaudal D Homolog 2 (BICD2))
    Alternative Name
    BICD2 (BICD2 Products)
    Synonyms
    SMALED2 antibody, bA526D8.1 antibody, 0610027D24Rik antibody, 1110005D12Rik antibody, AA408834 antibody, mKIAA0699 antibody, MGC84972 antibody, BICD2 antibody, bicd2 antibody, BICD cargo adaptor 2 antibody, bicaudal D homolog 2 (Drosophila) antibody, BICD cargo adaptor 2 L homeolog antibody, zgc:171572 antibody, BICD2 antibody, Bicd2 antibody, bicd2.L antibody, bicd2 antibody, zgc:171572 antibody
    Background

    Background: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).

    Aliases: bA526D8.1 antibody, Bic D 2 antibody, Bic-D 2 antibody, Bicaudal D homolog 2 (Drosophila) antibody, Bicaudal D homolog 2 antibody, Bicd2 antibody, BICD2_HUMAN antibody, Coiled coil protein BICD2 antibody, Cytoskeleton like bicaudal D protein homolog 2 antibody, Homolog of Drosophila bicaudal D antibody, KIAA0699 antibody, Protein bicaudal D homolog 2 antibody

    UniProt
    Q8TD16
    Pathways
    Maintenance of Protein Location
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