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CYR61 antibody (AA 25-381) (FITC)

CYR61 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7165240
$328.90
Plus shipping costs $45.00
Shipping to: United States
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  • Target See all CYR61 Antibodies
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-381
    Reactivity
    • 52
    • 35
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 51
    • 5
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYR61 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein CYR61 protein (25-381AA)
    Isotype
    IgG
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Alternative Name
    CYR61 (CYR61 Products)
    Synonyms
    CCN1 antibody, GIG1 antibody, IGFBP10 antibody, ccn1 antibody, gig1 antibody, Xcyr61 antibody, igfbp10 antibody, MGC69281 antibody, MGC69539 antibody, cyr61-l2 antibody, zgc:158158 antibody, CYR61 antibody, AI325051 antibody, Igfbp10 antibody, cysteine rich angiogenic inducer 61 antibody, cysteine-rich, angiogenic inducer, 61 antibody, cysteine-rich, angiogenic inducer, 61 like 2 antibody, cysteine rich protein 61 antibody, cysteine rich angiogenic inducer 61 S homeolog antibody, CYR61 antibody, Cyr61 antibody, cyr61 antibody, cyr61l2 antibody, cyr61.S antibody
    Background

    Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

    Aliases: 3CH61 antibody, CCN 1 antibody, CCN family member 1 antibody, CCN1 antibody, CYR 61 antibody, Cyr61 antibody, CYR61 protein antibody, CYR61_HUMAN antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich heparin binding protein 61 antibody, Cysteine-rich angiogenic inducer 61 antibody, GIG 1 antibody, GIG1 antibody, IBP-10 antibody, IGF-binding protein 10 antibody, Igfbp 10 antibody, IGFBP-10 antibody, Igfbp10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin-like growth factor-binding protein 10 antibody, Protein CYR61 antibody, Protein GIG1 antibody

    UniProt
    O00622
    Pathways
    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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