Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SBNO2 antibody (AA 6-146) (FITC)

SBNO2 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7166168
  • Target See all SBNO2 Antibodies
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Binding Specificity
    AA 6-146
    Reactivity
    Human
    Host
    • 4
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    This SBNO2 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
    Isotype
    IgG
    Top Product
    Discover our top product SBNO2 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Alternative Name
    SBNO2 (SBNO2 Products)
    Synonyms
    KIAA0963 antibody, SNO antibody, STNO antibody, BC019206 antibody, F730040C21 antibody, Sno antibody, Stno antibody, strawberry notch homolog 2 antibody, strawberry notch homolog 2 (Drosophila) antibody, SBNO2 antibody, Sbno2 antibody
    Background

    Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

    Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody

    UniProt
    Q9Y2G9
You are here: