UNC13D antibody (AA 7-172) (HRP)

Catalog No. ABIN7166252

This Rabbit Polyclonal antibody specifically detects UNC13D in ELISA. It exhibits reactivity toward Human.

Quick Overview for UNC13D antibody (AA 7-172) (HRP) (ABIN7166252)

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC13D antibody is conjugated to HRP

Application: ELISA

Product Details anti-UNC13D Antibody (HRP)

Binding Specificity: AA 7-172

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein unc-13 homolog D protein (7-172AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UNC13D

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Alternative Name: UNC13D

Background:

Background: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.

Aliases: FHL 3 antibody, FHL3 antibody, FLJ00067 antibody, HLH 3 antibody, HLH3 antibody, HPLH 3 antibody, HPLH3 antibody, Jinx antibody, Munc13 4 antibody, Munc13-4 antibody, Protein unc 13 homolog D antibody, Protein unc-13 homolog D antibody, UN13D_HUMAN antibody, Unc 13 homolog D antibody, UNC 13D antibody, Unc-13 homolog D (C. elegans) antibody, Unc13 homolog D (C elegans) antibody, Unc13 homolog D antibody, UNC13, C. elegans, homolog of, D antibody, UNC13D antibody, Unc13h4 antibody

UniProt: Q70J99

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process