RAB11B antibody (AA 2-215) (HRP)

Catalog No. ABIN7167228

The Rabbit Polyclonal anti-RAB11B antibody has been validated for ELISA. It is suitable to detect RAB11B in samples from Human.

Quick Overview for RAB11B antibody (AA 2-215) (HRP) (ABIN7167228)

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB11B antibody is conjugated to HRP

Application: ELISA

Product Details anti-RAB11B Antibody (HRP)

Binding Specificity: AA 2-215

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-11B protein (2-215AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAB11B

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Alternative Name: RAB11B

Background:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

Aliases: GTP binding protein YPT3 antibody, GTP-binding protein ypt3 antibody, H-YPT3 antibody, RAB 11A antibody, RAB11B antibody, RAB11B member RAS oncogene family antibody, RAB11B, member of RAS oncogene family antibody, Ras related protein Rab 11B antibody, RAS-associated protein RAB11B antibody, Ras-related protein Rab-11B antibody, RB11B_HUMAN antibody, YPT3 antibody

UniProt: Q15907

Pathways: Hormone Transport, Carbohydrate Homeostasis