RAB17 antibody (AA 1-212)

Catalog No. ABIN7167233

Product Details anti-RAB17 Antibody

Target: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Binding Specificity: AA 1-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ras-related protein Rab-17 protein (1-212AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAB17

Target: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Alternative Name: RAB17 (RAB17 Products)

Synonyms: RAB17 antibody, AW413472 antibody, RGD1562478 antibody, rab17 antibody, RAB17, member RAS oncogene family antibody, EDI_278050 antibody, EDI_260720 antibody, EDI_050010 antibody, RAB17 antibody, Rab17 antibody

Background:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Aliases: AW413472 antibody, FLJ12538 antibody, OTTHUMP00000164417 antibody, OTTHUMP00000202805 antibody, Rab 17 antibody, Rab17 antibody, RAB17 member RAS oncogene family antibody, RAB17_HUMAN antibody, Ras related protein Rab 17 antibody, Ras related protein Rab17 antibody, Ras-related protein Rab-17 antibody

UniProt: Q9H0T7