RMI1 antibody (AA 181-443)

Catalog No. ABIN7167546

The Rabbit Polyclonal anti-RMI1 antibody is suitable to detect RMI1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for RMI1 antibody (AA 181-443) (ABIN7167546)

Target: RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RMI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RMI1 Antibody

Binding Specificity: AA 181-443

Purpose: RMI1 Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human RecQ-mediated genome instability protein 1 protein (181-443AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RMI1

Target: RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))

Alternative Name: RMI1

Background:

Background: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

Aliases: BLAP75 antibody, BLM associated polypeptide 75 kDa antibody, BLM associated protein 75 kDa antibody, BLM-associated protein of 75 kDa antibody, C9orf76 antibody, FAAP75 antibody, FLJ12888 antibody, Homolog of yeast RecQ mediated genome instability 1 antibody, RecQ mediated genome instability 1 antibody, RecQ-mediated genome instability protein 1 antibody, Rmi1 antibody, RMI1 homolog antibody, RMI1 RecQ mediated genome instability 1 homolog antibody, RMI1_HUMAN antibody, RP11-346I8 antibody

UniProt: Q9H9A7

Pathways: DNA Damage Repair