PDE6D antibody (AA 1-150)

Catalog No. ABIN7167776

This Rabbit Polyclonal antibody specifically detects PDE6D in ELISA, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for PDE6D antibody (AA 1-150) (ABIN7167776)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PDE6D Antibody

Binding Specificity: AA 1-150

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Retinal rod rhodopsin-sensitive cGMP 3\\\',5\\\'-cyclic phosphodiesterase subunit delta protein (1-150AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D

Background:

Background: Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).

Aliases: 5''-cyclic phosphodiesterase subunit delta antibody, GMP PDE delta antibody, GMP-PDE delta antibody, p17 protein antibody, PDE 6 antibody, PDE 6D antibody, PDE D antibody, PDE6 antibody, PDE6D antibody, PDE6D_HUMAN antibody, PDED antibody, Phosphodiesterase 6D cGMP specific antibody, Phosphodiesterase 6D cGMP specific rod delta antibody, Protein p17 antibody, Retinal rod photoreceptor cGMP phosphodiesterase delta antibody, Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta antibody, Retinal rod rhodopsin-sensitive cGMP 3'' antibody

UniProt: O43924