Retinoic Acid Receptor beta antibody (AA 1-85) (Biotin)

Catalog No. ABIN7167800

This Rabbit Polyclonal antibody specifically detects Retinoic Acid Receptor beta in ELISA. It exhibits reactivity toward Human.

Quick Overview for Retinoic Acid Receptor beta antibody (AA 1-85) (Biotin) (ABIN7167800)

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoic Acid Receptor beta antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Retinoic Acid Receptor beta Antibody (Biotin)

Binding Specificity: AA 1-85

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Retinoic acid receptor beta protein (1-85AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Alternative Name: RARB

Background:

Background: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5\'-AGGTCA-3\' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Aliases: HAP antibody, HBV-activated protein antibody, NR1B2 antibody, Nuclear receptor subfamily 1 group B member 2 antibody, RAR B antibody, RAR beta antibody, RAR epsilon antibody, RAR-beta antibody, RAR-epsilon antibody, RARB antibody, RARB_HUMAN antibody, Retinoic acid receptor beta 2 antibody, Retinoic acid receptor beta 4 antibody, Retinoic acid receptor beta 5 antibody, Retinoic acid receptor beta antibody, Retinoic acid receptor beta polypeptide antibody, RRB2 antibody

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway