RNASEH2C antibody (AA 1-164)

Catalog No. ABIN7168111

Product Details anti-RNASEH2C Antibody

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Binding Specificity: AA 1-164

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNASEH2C

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Alternative Name: RNASEH2C (RNASEH2C Products)

Synonyms: AGS3 antibody, AYP1 antibody, 1500026D16Rik antibody, ribonuclease H2 subunit C antibody, ribonuclease H2, subunit C antibody, RNASEH2C antibody, Rnaseh2c antibody

Background:

Background: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Aliases: RNASEH2C antibody, AYP1 antibody, Ribonuclease H2 subunit C antibody, RNase H2 subunit C antibody, Aicardi-Goutieres syndrome 3 protein antibody, AGS3 antibody, RNase H1 small subunit antibody, Ribonuclease HI subunit C antibody

UniProt: Q8TDP1