RCHY1 antibody (AA 1-261)

Catalog No. ABIN7168232

Product Details anti-RCHY1 Antibody

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Binding Specificity: AA 1-261

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCHY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human RING finger and CHY zinc finger domain-containing protein 1 protein (1-261AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RCHY1

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Alternative Name: RCHY1 (RCHY1 Products)

Synonyms: ARNIP antibody, CHIMP antibody, PIRH2 antibody, PRO1996 antibody, RNF199 antibody, ZNF363 antibody, Pirh2 antibody, Zfp363 antibody, Znf363 antibody, wu:fb37e07 antibody, zgc:101128 antibody, RCHY1 antibody, arnip antibody, chimp antibody, pirh2 antibody, harnip antibody, rnf199 antibody, znf363 antibody, pro1996 antibody, ring finger and CHY zinc finger domain containing 1 antibody, ring finger and CHY zinc finger domain containing 1 L homeolog antibody, RCHY1 antibody, Rchy1 antibody, rchy1 antibody, rchy1.L antibody

Background:

Background: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.

Aliases: Androgen receptor N terminal interacting protein antibody, Androgen receptor N-terminal-interacting protein antibody, ARNIP antibody, CH-rich-interacting match with PLAG1 antibody, CHIMP antibody, E3 ubiquitin-protein ligase Pirh2 antibody, hARNIP antibody, hPirh2 antibody, p53 induced protein with a RING H2 domain antibody, p53-induced RING-H2 protein antibody, PIRH2E antibody, PIRH2F antibody, PRO1996 antibody, RCHY1 antibody, Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody, RING finger and CHY zinc finger domain-containing protein 1 antibody, RING finger protein 199 antibody, RNF199 antibody, ZCHY antibody, ZFP 363 antibody, zinc finger CHY type antibody, Zinc finger protein 363 antibody, ZN363_HUMAN antibody, ZNF363 antibody

UniProt: Q96PM5