RBM38 antibody (AA 1-239)

Catalog No. ABIN7168341

The Rabbit Polyclonal anti-RBM38 antibody has been validated for ELISA, IHC and IF. It is suitable to detect RBM38 in samples from Human.

Quick Overview for RBM38 antibody (AA 1-239) (ABIN7168341)

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM38 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RBM38 Antibody

Binding Specificity: AA 1-239

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human RNA-binding protein 38 protein (1-239AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RBM38

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Alternative Name: RBM38

Background:

Background: RNA-binding protein that specifically bind the 3\'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Aliases: CLL associated antigen KW 5 antibody, CLL-associated antigen KW-5 antibody, HSRNASEB antibody, RBM38 antibody, RBM38_HUMAN antibody, RNA binding motif protein 38 antibody, RNA binding protein 38 antibody, RNA binding region (RNP1, RRM) containing 1 antibody, RNA binding region containing protein 1 antibody, RNA-binding motif protein 38 antibody, RNA-binding protein 38 antibody, RNA-binding region-containing protein 1 antibody, RNPC1 antibody, SEB4 antibody, SEB4B antibody, SEB4D antibody, ssDNA binding protein SEB4 antibody, ssDNA-binding protein SEB4 antibody

UniProt: Q9H0Z9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development