SEMA4D/CD100 antibody (AA 756-862) (HRP)

Catalog No. ABIN7168806

The Rabbit Polyclonal anti-SEMA4D/CD100 antibody is suitable to detect SEMA4D/CD100 in samples from Human. It has been validated for ELISA.

Quick Overview for SEMA4D/CD100 antibody (AA 756-862) (HRP) (ABIN7168806)

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA4D/CD100 antibody is conjugated to HRP

Application: ELISA

Product Details anti-SEMA4D/CD100 Antibody (HRP)

Binding Specificity: AA 756-862

Purpose: SEMA4D Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Semaphorin-4D protein (756-862AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SEMA4D/CD100

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Alternative Name: SEMA4D

Background:

Background: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Aliases: A8 antibody, BB 18 antibody, BB18 antibody, CD 100 antibody, CD100 antibody, CD100 antigen antibody, Coll 4 antibody, COLL4 antibody, Collapsin 4 antibody, Collapsin4 antibody, GR3 antibody, Leukocyte activation antigen CD100 antibody, M sema G antibody, MSEMA antibody, SEM4D_HUMAN antibody, Sema 4d antibody, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D antibody, Sema H antibody, SEMA J antibody, Sema4d antibody, Semacl 2 antibody, Semacl2 antibody, SemaH antibody, SEMAJ antibody, Semaphorin 4D antibody, Semaphorin C like 2 antibody, Semaphorin H antibody, Semaphorin J antibody, Semaphorin-4D antibody, Semaphorin4D antibody, SemaphorinJ antibody, Semcl 2 antibody, Semcl2 antibody

UniProt: Q92854

Pathways: Regulation of Cell Size