SENP1 antibody (AA 63-214)

Catalog No. ABIN7168833

The Rabbit Polyclonal anti-SENP1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect SENP1 in samples from Human.

Quick Overview for SENP1 antibody (AA 63-214) (ABIN7168833)

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SENP1 Antibody

Binding Specificity: AA 63-214

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sentrin-specific protease 1 protein (63-214AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SENP1

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Alternative Name: SENP1

Background:

Background: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032).

Aliases: SENP 1 antibody, SENP1 antibody, SENP1_HUMAN antibody, Sentrin specific protease 1 antibody, Sentrin-specific protease 1 antibody, Sentrin/SUMO specific protease 1 antibody, Sentrin/SUMO specific protease antibody, Sentrin/SUMO specific protease SENP 1 antibody, Sentrin/SUMO specific protease SENP1 antibody, Sentrin/SUMO-specific protease SENP1 antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific protease 1 antibody, SuPr 2 antibody, SuPr2 antibody

UniProt: Q9P0U3

Pathways: Positive Regulation of Endopeptidase Activity