STK24 antibody (AA 1-431)

Catalog No. ABIN7168982

This Rabbit Polyclonal antibody specifically detects STK24 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for STK24 antibody (AA 1-431) (ABIN7168982)

Target: STK24 (serine/threonine Kinase 24 (STK24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK24 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STK24 Antibody

Binding Specificity: AA 1-431

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein kinase 24 protein (1-431AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STK24

Target: STK24 (serine/threonine Kinase 24 (STK24))

Alternative Name: STK24

Background:

Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on \\\'Thr-442\\\' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Aliases: epididymis secretory protein Li 95 antibody, HEL-S-95 antibody, Mammalian STE20 like protein kinase 3 antibody, Mammalian STE20-like protein kinase 3 antibody, Mammalian STE20-like protein kinase 3 C-terminal antibody, Mammalian STE20-like protein kinase 3 N-terminal antibody, Mammalian sterile 20-like 3 antibody, MST-3 antibody, MST3/C antibody, MST3/N antibody, MST3B antibody, serine threonine kinase 24 antibody, Serine/threonine kinase 24 (Ste20, yeast homolog) antibody, Serine/threonine-protein kinase 24 12 kDa subunit antibody, Serine/threonine-protein kinase 24 antibody, STE20 homolog yeast antibody, STE20 like kinase MST3 antibody, STE20-like kinase MST3 antibody, Stk24 antibody, STK24_HUMAN antibody, STK3 antibody

UniProt: Q9Y6E0