SESN3 antibody (AA 1-310)

Catalog No. ABIN7169409

The Rabbit Polyclonal anti-SESN3 antibody has been validated for ELISA and IHC. It is suitable to detect SESN3 in samples from Human.

Quick Overview for SESN3 antibody (AA 1-310) (ABIN7169409)

Target: SESN3 (Sestrin 3 (SESN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-SESN3 Antibody

Binding Specificity: AA 1-310

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Sestrin-3 protein (1-310AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: SESN3

Background:

Background: Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity.

Aliases: MGC29667 antibody, OTTHUMP00000236979 antibody, OTTHUMP00000236986 antibody, SESN3 antibody, SESN3_HUMAN antibody, SEST3 antibody, Sestrin 3 antibody, Sestrin-3 antibody

UniProt: P58005