TMEM66 antibody (AA 195-339) (Biotin)

Catalog No. ABIN7170808

Product Details anti-TMEM66 Antibody (Biotin)

Target: TMEM66 (Transmembrane Protein 66 (TMEM66))

Binding Specificity: AA 195-339

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM66 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Store-operated calcium entry-associated regulatory factor protein (195-339AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMEM66

Target: TMEM66 (Transmembrane Protein 66 (TMEM66))

Alternative Name: SARAF (TMEM66 Products)

Synonyms: FOAP-7 antibody, SARAF antibody, XTP3 antibody, 1810045K07Rik antibody, tmem66 antibody, Tmem66 antibody, TMEM66 antibody, store-operated calcium entry associated regulatory factor antibody, store-operated calcium entry-associated regulatory factor antibody, store-operated calcium entry-associated regulatory factor S homeolog antibody, transmembrane protein 66 antibody, SARAF antibody, Saraf antibody, saraf antibody, saraf.S antibody, MCYG_05410 antibody, MGYG_06464 antibody, Tsp_10089 antibody

Background:

Background: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

Aliases: FLJ22274 antibody, FOAP 7 antibody, HBV X transactivated gene 3 protein antibody, HBV X-transactivated gene 3 protein antibody, HBV XAg-transactivated protein 3 antibody, HSPC035 antibody, MGC8721 antibody, Protein FOAP 7 antibody, Protein FOAP-7 antibody, TMEM 66 antibody, Tmem66 antibody, TMM66_HUMAN antibody, Transmembrane protein 66 antibody, XTP3 antibody

UniProt: Q96BY9