SDHAF1 antibody (AA 78-115) (Biotin)

Catalog No. ABIN7170895

Product Details anti-SDHAF1 Antibody (Biotin)

Target: SDHAF1 (Succinate Dehydrogenase Complex Assembly Factor 1 (SDHAF1))

Binding Specificity: AA 78-115

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHAF1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Succinate dehydrogenase assembly factor 1, mitochondrial protein (78-115AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SDHAF1

Target: SDHAF1 (Succinate Dehydrogenase Complex Assembly Factor 1 (SDHAF1))

Alternative Name: SDHAF1 (SDHAF1 Products)

Synonyms: Lyrm8 antibody, Sdhaf1 antibody, LYRM8 antibody, 0610010E21Rik antibody, AI430885 antibody, AW490662 antibody, succinate dehydrogenase complex assembly factor 1 antibody, SDHAF1 antibody, Sdhaf1 antibody

Background:

Background: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF3.

Aliases: LYR motif containing 8 antibody, LYR motif-containing protein 8 antibody, LYRM8 antibody, mitochondrial antibody, SDH assembly factor 1 antibody, SDHAF1 antibody, SDHF1_HUMAN antibody, Succinate dehydrogenase assembly factor 1 antibody, Succinate dehydrogenase assembly factor 1 mitochondrial antibody, Succinate dehydrogenase complex assembly factor 1 antibody

UniProt: A6NFY7