SOCS2 antibody (AA 1-198)

Catalog No. ABIN7170995

This Rabbit Polyclonal antibody specifically detects SOCS2 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SOCS2 antibody (AA 1-198) (ABIN7170995)

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SOCS2 Antibody

Binding Specificity: AA 1-198

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SOCS2

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Alternative Name: SOCS2

Background:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Aliases: CIS 2 antibody, CIS-2 antibody, CIS2 antibody, Cish 2 antibody, Cish2 antibody, Cytokine inducible SH2 protein 2 antibody, Cytokine-inducible SH2 protein 2 antibody, SOCS 2 antibody, SOCS-2 antibody, Socs2 antibody, SOCS2_HUMAN antibody, SSI 2 antibody, SSI-2 antibody, SSI2 antibody, STAT induced STAT inhibitor 2 antibody, STAT-induced STAT inhibitor 2 antibody, STATI 2 antibody, STATI2 antibody, Suppressor of cytokine signaling 2 antibody

UniProt: O14508

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus