Tenascin N antibody (AA 441-556) (HRP)

Catalog No. ABIN7171749

The Rabbit Polyclonal anti-Tenascin N antibody has been validated for ELISA. It is suitable to detect Tenascin N in samples from Human.

Quick Overview for Tenascin N antibody (AA 441-556) (HRP) (ABIN7171749)

Target: Tenascin N (TNN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin N antibody is conjugated to HRP

Application: ELISA

Product Details anti-Tenascin N Antibody (HRP)

Binding Specificity: AA 441-556

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tenascin-N protein (441-556AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Tenascin N

Target: Tenascin N (TNN)

Alternative Name: TNN

Background:

Background: Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).

Aliases: TNN antibody, TNW antibody, Tenascin-N antibody, TN-N antibody, Tenascin-W antibody, TN-W antibody

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway