Tenascin N antibody

Catalog No. ABIN7231754

This Rabbit Polyclonal antibody specifically detects Tenascin N in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Tenascin N antibody (ABIN7231754)

Target: Tenascin N (TNN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin N antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Tenascin N Antibody

Purpose: Rabbit Anti-TENN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TENN protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TENN protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Tenascin N

Target: Tenascin N (TNN)

Alternative Name: TENN

Background: Tenascin-N, TN-N, Tenascin-W, TN-WTNN (Tenascin N) is a Protein Coding gene. Diseases associated with TNN include Adhesive Otitis Media and Chronic Purulent Otitis Media. Among its related pathways are ECM proteoglycans and Focal Adhesion. Extracellular matrix protein that seems to be a ligand for ITGA8: ITGB1, ITGAV: ITGB1 and ITGA4: ITGB1. Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells.

Molecular Weight: 142kD

Gene ID: 63923

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway