TAB3 antibody (AA 361-712)

Catalog No. ABIN7171966

This anti-TAB3 antibody is a Rabbit Polyclonal antibody detecting TAB3 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for TAB3 antibody (AA 361-712) (ABIN7171966)

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAB3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TAB3 Antibody

Binding Specificity: AA 361-712

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 protein (361-712AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TAB3

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Alternative Name: TAB3

Background:

Background: Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.

Aliases: MAP3K7IP 3 antibody, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 antibody, NAP1 antibody, NF-kappa-B-activating protein 1 antibody, NFkB activating protein 1 antibody, TAB-3 antibody, Tab3 antibody, TAB3_HUMAN antibody, TAK1 binding protein 3 antibody, TAK1-binding protein 3 antibody, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 antibody, TGF-beta-activated kinase 1-binding protein 3 antibody

UniProt: Q8N5C8

Pathways: TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades