TLR3 antibody (AA 135-297) (Biotin)

Catalog No. ABIN7172271

The Rabbit Polyclonal anti-TLR3 antibody has been validated for ELISA. It is suitable to detect TLR3 in samples from Human.

Quick Overview for TLR3 antibody (AA 135-297) (Biotin) (ABIN7172271)

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TLR3 Antibody (Biotin)

Binding Specificity: AA 135-297

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Toll-like receptor 3 protein (135-297AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLR3

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Alternative Name: TLR3

Background:

Background: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.

Aliases: CD283 antibody, CD283 antigen antibody, IIAE2 antibody, TLR 3 antibody, Tlr3 antibody, TLR3_HUMAN antibody, Toll Like Receptor 3 antibody, Toll-like receptor 3 antibody

UniProt: O15455

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades