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TLR3 antibody (C-Term)

TLR3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265599
  • Target See all TLR3 Antibodies
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Binding Specificity
    • 16
    • 9
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 98
    • 65
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 85
    • 31
    • 3
    • 2
    Rabbit
    Clonality
    • 88
    • 33
    Polyclonal
    Conjugate
    • 53
    • 18
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR3 antibody is un-conjugated
    Application
    • 84
    • 43
    • 37
    • 34
    • 24
    • 18
    • 15
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    TLR3 Antibody detects endogenous levels of total TLR3.
    Predicted Reactivity
    Bovine,Horse,Sheep,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TLR3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TLR3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Alternative Name
    TLR3 (TLR3 Products)
    Synonyms
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    Background

    Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.

    Gene: TLR3

    Molecular Weight
    99kDa
    Gene ID
    7098
    UniProt
    O15455
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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