DP2 antibody (AA 344-386)

Catalog No. ABIN7172505

The Rabbit Polyclonal anti-DP2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect DP2 in samples from Human.

Quick Overview for DP2 antibody (AA 344-386) (ABIN7172505)

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DP2 Antibody

Binding Specificity: AA 344-386

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transcription factor Dp-2 protein (344-386AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DP2

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Alternative Name: TFDP2

Background:

Background: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).

Aliases: DP2 antibody, E2F dimerization partner 2 antibody, Tfdp2 antibody, TFDP2_HUMAN antibody, Transcription factor Dp 2 antibody, Transcription factor Dp-2 antibody

UniProt: Q14188

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases