TRAPPC10 antibody (AA 1-55) (Biotin)

Catalog No. ABIN7173020

This Rabbit Polyclonal antibody specifically detects TRAPPC10 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TRAPPC10 antibody (AA 1-55) (Biotin) (ABIN7173020)

Target: TRAPPC10 (TMEM1) (Transmembrane Protein 1 (TMEM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAPPC10 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TRAPPC10 Antibody (Biotin)

Binding Specificity: AA 1-55

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transmembrane protein 100 protein (1-55AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRAPPC10

Target: TRAPPC10 (TMEM1) (Transmembrane Protein 1 (TMEM1))

Alternative Name: TMEM1

Background:

Background: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.

Aliases: TMEM100 antibody, Transmembrane protein 100 antibody

UniProt: Q9NV29