TNRC6B antibody (AA 639-779)

Catalog No. ABIN7173403

Product Details anti-TNRC6B Antibody

Target: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Binding Specificity: AA 639-779

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNRC6B antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Trinucleotide repeat-containing gene 6B protein (639-779AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TNRC6B

Target: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Alternative Name: TNRC6B (TNRC6B Products)

Synonyms: hm:zeh0114 antibody, im:6968518 antibody, wu:fa01f05 antibody, 2700090M07Rik antibody, A730065C02Rik antibody, AI848765 antibody, D230019K20Rik antibody, Cbl27 antibody, trinucleotide repeat containing 6b antibody, trinucleotide repeat containing 6B antibody, trinucleotide repeat containing 6B S homeolog antibody, tnrc6b antibody, TNRC6B antibody, tnrc6b.S antibody, Tnrc6b antibody

Background:

Background: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Aliases: TNRC6B antibody, KIAA1093 antibody, Trinucleotide repeat-containing gene 6B protein antibody

UniProt: Q9UPQ9

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway