TSC22D3 antibody (AA 58-134) (HRP)

Catalog No. ABIN7173629

This Rabbit Polyclonal antibody specifically detects TSC22D3 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TSC22D3 antibody (AA 58-134) (HRP) (ABIN7173629)

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D3 antibody is conjugated to HRP

Application: ELISA

Product Details anti-TSC22D3 Antibody (HRP)

Binding Specificity: AA 58-134

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TSC22 domain family protein 3 protein (58-134AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Alternative Name: TSC22D3

Background:

Background: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.

Aliases: Delta sleep-inducing peptide immunoreactor antibody, DIP antibody, DSIP immunoreactive leucine zipper protein antibody, DSIP-immunoreactive peptide antibody, Dsip1 antibody, Dsipi antibody, GILZ antibody, Glucocorticoid-induced leucine zipper protein antibody, hDIP antibody, Protein DIP antibody, T22D3_HUMAN antibody, TSC-22-like protein antibody, TSC-22-related protein antibody, TSC-22R antibody, TSC22 domain family protein 3 antibody, TSC22 domain family, member 3 antibody, TSC22 related inducible leucine zipper 3 antibody, TSC22D3 antibody

UniProt: Q99576