TNFRSF10A antibody (AA 263-468) (Biotin)

Catalog No. ABIN7173826

The Biotin-conjugated Rabbit Polyclonal anti-TNFRSF10A antibody (ABIN7173826) specifically detects TNFRSF10A in ELISA. The antibody is reactive with Human samples.

Quick Overview for TNFRSF10A antibody (AA 263-468) (Biotin) (ABIN7173826)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10A antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TNFRSF10A Antibody (Biotin)

Binding Specificity: AA 263-468

Purpose: TNFRSF10A Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 10A protein (263-468AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TNFRSF10A

Background:

Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Aliases: Apo2 antibody, CD261 antibody, Cytotoxic TRAIL receptor antibody, Death receptor 4 antibody, DR4 antibody, NF related apoptosis-inducing ligand receptor 1 antibody, TNF receptor superfamily member 10a antibody, TNF-related apoptosis-inducing ligand receptor 1 antibody, TNFRSF10A antibody, TR10A_HUMAN antibody, TRAIL receptor 1 antibody, TRAIL-R1 antibody, TRAILR 1 antibody, TRAILR1 antibody, Tumor necrosis factor receptor superfamily member 10A antibody, Tumor necrosis factor receptor superfamily member 10a variant 2 antibody, Tumor necrosis factor receptor superfamily, member 10a antibody

UniProt: O00220

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity