FAS antibody (AA 26-171)

Catalog No. ABIN7173891

The Rabbit Polyclonal anti-FAS antibody has been validated for IHC, ELISA and IF. It is suitable to detect FAS in samples from Human.

Quick Overview for FAS antibody (AA 26-171) (ABIN7173891)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAS antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-FAS Antibody

Binding Specificity: AA 26-171

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (26-171AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: FAS

Background:

Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Aliases: ALPS 1A antibody, ALPS1A antibody, APO 1 antibody, Apo 1 antigen antibody, APO 1 cell surface antigen antibody, Apo-1 antigen antibody, APO1 antibody, Apo1 antigen antibody, APO1 cell surface antigen antibody, Apoptosis antigen 1 antibody, Apoptosis mediating surface antigen FAS antibody, Apoptosis-mediating surface antigen FAS antibody, APT 1 antibody, APT1 antibody, CD 95 antibody, CD 95 antigen antibody, CD95 antibody, CD95 antigen antibody, Delta Fas antibody, Delta Fas/APO 1/CD95 antibody, Delta Fas/APO1/CD95 antibody, Fas (TNF receptor superfamily, member 6) antibody, FAS 1 antibody, FAS 827dupA antibody, Fas AMA antibody, Fas antibody, FAS Antigen antibody, Fas cell surface death receptor antibody, FAS1 antibody, FASLG receptor antibody, FASTM antibody, sFAS antibody, Surface antigen APO1 antibody, TNF receptor superfamily, member 6 antibody, TNFRSF 6 antibody, TNFRSF6 antibody, TNR6_HUMAN antibody, Tumor necrosis factor receptor superfamily member 6 antibody

UniProt: P25445

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity