TWIST2 antibody (AA 1-70)

Catalog No. ABIN7173949

This anti-TWIST2 antibody is a Rabbit Polyclonal antibody detecting TWIST2 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for TWIST2 antibody (AA 1-70) (ABIN7173949)

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TWIST2 Antibody

Binding Specificity: AA 1-70

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Twist-related protein 2 protein (1-70AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Alternative Name: TWIST2

Background:

Background: Binds to the E-box consensus sequence 5\\\'-CANNTG-3\\\' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Aliases: bHLHa39 antibody, Class A basic helix-loop-helix protein 39 antibody, Dermis expressed protein 1 antibody, Dermis-expressed protein 1 antibody, DERMO 1 antibody, Dermo-1 antibody, DERMO1 antibody, MGC117334 antibody, Twist 2 antibody, Twist homolog 2 (Drosophila) antibody, Twist homolog 2 antibody, Twist related bHLH protein Dermo1 antibody, Twist related protein 2 antibody, Twist-related protein 2 antibody, Twist2 antibody, TWST2_HUMAN antibody

UniProt: Q8WVJ9

Pathways: Chromatin Binding