UBA6 antibody (AA 1-44)

Catalog No. ABIN7174530

Product Details anti-UBA6 Antibody

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Binding Specificity: AA 1-44

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-like modifier-activating enzyme 6 protein (1-44AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBA6

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Alternative Name: UBA6 (UBA6 Products)

Synonyms: E1-L2 antibody, MOP-4 antibody, UBE1L2 antibody, 4930542H01 antibody, 5730469D23Rik antibody, AU021846 antibody, AW124799 antibody, Ube1l2 antibody, RGD1308324 antibody, ubiquitin like modifier activating enzyme 6 antibody, ubiquitin-like modifier activating enzyme 6 antibody, UBA6 antibody, Uba6 antibody

Background:

Background: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.

Aliases: E1-L2 antibody, FLJ10808 antibody, FLJ23367 antibody, Monocyte protein 4 antibody, MOP 4 antibody, MOP-4 antibody, MOP4 antibody, UBA 6 antibody, Uba6 antibody, UBA6 ubiquitin activating enzyme E1 antibody, UBA6_HUMAN antibody, UBE1L2 antibody, Ubiquitin activating enzyme 6 antibody, Ubiquitin activating enzyme E1 like 2 antibody, Ubiquitin activating enzyme E1 like protein 2 antibody, Ubiquitin like modifier activating enzyme 6 antibody, Ubiquitin-activating enzyme 6 antibody, Ubiquitin-activating enzyme E1-like protein 2 antibody, Ubiquitin-like modifier-activating enzyme 6 antibody

UniProt: A0AVT1