MYO1G antibody (AA 209-389)

Catalog No. ABIN7174949

Product Details anti-MYO1G Antibody

Target: MYO1G (Myosin IG (MYO1G))

Binding Specificity: AA 209-389

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO1G antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-Ig protein (209-389AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYO1G

Target: MYO1G (Myosin IG (MYO1G))

Alternative Name: MYO1G (MYO1G Products)

Synonyms: HA2 antibody, MHAG antibody, E430002D17Rik antibody, myosin IG antibody, MYO1G antibody, Myo1g antibody

Background:

Background: Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.

Aliases: mHag HA-2 antibody, Minor histocompatibility antigen HA-2 antibody, Myo1g antibody, MYO1G_HUMAN antibody, myosin IG antibody

UniProt: B0I1T2