MYO1G antibody (AA 209-389) (Biotin)

Catalog No. ABIN7174950

The Rabbit Polyclonal anti-MYO1G antibody has been validated for ELISA. It is suitable to detect MYO1G in samples from Human.

Quick Overview for MYO1G antibody (AA 209-389) (Biotin) (ABIN7174950)

Target: MYO1G (Myosin IG (MYO1G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO1G antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MYO1G Antibody (Biotin)

Binding Specificity: AA 209-389

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-Ig protein (209-389AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYO1G

Target: MYO1G (Myosin IG (MYO1G))

Alternative Name: MYO1G

Background:

Background: Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.

Aliases: mHag HA-2 antibody, Minor histocompatibility antigen HA-2 antibody, Myo1g antibody, MYO1G_HUMAN antibody, myosin IG antibody

UniProt: B0I1T2