MYO5B antibody (AA 1440-1690)
Quick Overview for MYO5B antibody (AA 1440-1690) (ABIN7174957)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1440-1690
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Unconventional myosin-Vb protein (1440-1690AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MYO5B (Myosin VB (MYO5B))
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Alternative Name
- MYO5B
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Background
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Background: May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
Aliases: KIAA1119 antibody, Myo5b antibody, MYO5B_HUMAN antibody, Myosin Vb antibody, Unconventional myosin-Vb antibody
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UniProt
- Q9ULV0
Target
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